Coccidiosis vaccines must be maintained at storage temperatures between 3°C and 7°C (38°F and 45°F).
Some coccidiosis vaccine manufacturers aim to compensate for the coccidia's limited lifespan by increasing the number of oocysts per dose. However, this is technically not possible since all the sporulated oocysts start off with roughly the same amount of energy source (amylopectin). It also increases the risk of severe post-vaccination reactions, especially if the vaccine is used too soon after manufacturing, resulting in too many infectable oocysts per dose being administered.